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p-pbpk model  (Simcyp)

 
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    Simcyp p-pbpk model
    P Pbpk Model, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p-pbpk model/product/Simcyp
    Average 90 stars, based on 1 article reviews
    p-pbpk model - by Bioz Stars, 2026-06
    90/100 stars

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    P‐PBPK modeling software (application areas, drugs, and major funding)

    Journal: CPT: Pharmacometrics & Systems Pharmacology

    Article Title: Predicting the correct dose in children: Role of computational Pediatric Physiological‐based pharmacokinetics modeling tools

    doi: 10.1002/psp4.12883

    Figure Lengend Snippet: P‐PBPK modeling software (application areas, drugs, and major funding)

    Article Snippet: Miao Zhang et al. developed a P‐PBPK model of HCQ using Simcyp (version 9.5) and integrated antiviral effects into vitro.

    Techniques: Software, Selection

    P‐PBPK modeling software (application areas, drugs, and major funding)

    Journal: CPT: Pharmacometrics & Systems Pharmacology

    Article Title: Predicting the correct dose in children: Role of computational Pediatric Physiological‐based pharmacokinetics modeling tools

    doi: 10.1002/psp4.12883

    Figure Lengend Snippet: P‐PBPK modeling software (application areas, drugs, and major funding)

    Article Snippet: In addition, in 2021, in the Bonner et al. work, the hydrocortisone P‐PBPK model developed in Simcyp (version 16.1) investigated the clinical dosing regimens.

    Techniques: Software, Selection

    Basic structure of p-PBPK model in (A) Gatsroplus (B) SimCyp and (C) Open Systems Pharmacology .

    Journal: Frontiers in Pediatrics

    Article Title: Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models

    doi: 10.3389/fped.2021.733823

    Figure Lengend Snippet: Basic structure of p-PBPK model in (A) Gatsroplus (B) SimCyp and (C) Open Systems Pharmacology .

    Article Snippet: However, in the Open Systems Pharmacology software package, each of these units are considered discrete and accounted for separately, along with the inclusion of myometrium and endometrium, as seen in . summarizes the physiological parameters that are considered in the Simcyp p-PBPK model.

    Techniques:

    Physiological parameters that are modified for pregnancy prediction in Simcyp p-PBPK model.

    Journal: Frontiers in Pediatrics

    Article Title: Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models

    doi: 10.3389/fped.2021.733823

    Figure Lengend Snippet: Physiological parameters that are modified for pregnancy prediction in Simcyp p-PBPK model.

    Article Snippet: However, in the Open Systems Pharmacology software package, each of these units are considered discrete and accounted for separately, along with the inclusion of myometrium and endometrium, as seen in . summarizes the physiological parameters that are considered in the Simcyp p-PBPK model.

    Techniques: Modification, Activity Assay

    Review of published p-PBPK models.

    Journal: Frontiers in Pediatrics

    Article Title: Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models

    doi: 10.3389/fped.2021.733823

    Figure Lengend Snippet: Review of published p-PBPK models.

    Article Snippet: However, in the Open Systems Pharmacology software package, each of these units are considered discrete and accounted for separately, along with the inclusion of myometrium and endometrium, as seen in . summarizes the physiological parameters that are considered in the Simcyp p-PBPK model.

    Techniques: Software, Activity Assay, In Vivo, Inhibition, Concentration Assay